Hi,
it depends on which client technology you are going to use. In Flash for example you can do that pretty easily by using our RedBox add-on which provides audio and video streaming.
See here: http://www.smartfoxserver.com/products/redbox
For other technologies such as Unity or native iOS and Android it would be best to look into a specific Media Server such as Wowza:
http://www.wowza.com/
Real-time audio
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